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As there is no 'golden' test, patients with clear neurological symptoms, and no other obvious cause for those problems, should be treated with B12 injections.
Insufficient or no intrinsic factor due to: autoimmune pernicious anaemia, ... Macrocytosis for example is not specific to a vitamin B deficiency in children and also ...
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A large number of patients however has no anaemia or macrocytosis so this should not stand in the way of a correct diagnosis. Intrinsic factor. Vitamin B12 can ...
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